A retrospective study examined the impact of overactive thyroid (Hyperthyroidism) on pregnancy outcomes on the mother and the newborn. The study lasted for 28 years and it included about 200 women with Hyperthyroidism and – 400 women as control group. Rates of pregnancy and birth complications such as preeclampsia (preeclampsia), growth retardation of – IUI (intrauterine growth restriction, IUGR) and preterm birth were higher among women with hyperthyroidism compared with the control group. Moreover, complications became worse in women with uncontrolled disease and women diagnosed with Hyperthyroidism during pregnancy.
There are few data bases comparing pregnancy outcomes of women with overactive thyroid (Hyperthyroidism) to other conditions.
This study was performed to evaluate the results of the mother and the newborn of pregnant women with Hyperthyroidism so researchers could determine the impact of this condition on pregnancy.
Researchers conducted a retrospective study lasting 28 years.
The researchers compared women with morning sickness, women with uncontrolled disease and women diagnosed with Hyperthyroidism before or during pregnancy.
Researchers examined the mother and the newborn results on 208 women with Hyperthyroidism and 403 women in the control group.
Women with Hyperthyroidism were at increased risk of pre-eclampsia (preeclampsia) (Odds Ratio = 3.94), growth retardation intra – uterine (intrauterine growth restriction, IUGR) (2.16), spontaneous premature birth (spontaneous preterm labor (s) 1.7), gestational diabetes (gestational diabetes mellitus) ( 1.8 ), and cesarean delivery (OR = 1.47).
Women with Hyperthyroidism need more frequent birth induction (OR = 3.61) .
Newborns to mothers with Hyperthyroidism had lower weight compared to women without the condition (p = 0.0001).
Women with uncontrolled disease had a higher odds of having a still birth (OR = 8.42 , 95 % CI 2.01 to 35.2) and lower birth weight (p = 0.0001).
- The rate of birth complications was higher in women with Hyperthyroidism than women without the condition.
- The results were worse in women with uncontrolled disease.
- Women with Hyperthyroidism discovered before pregnancy had better results than those diagnosed with Hyperthyroidism during pregnancy.